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M B Pepys Selected Research

Serum Amyloid P-Component

5/2002Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis.
7/2001Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein.
12/2000Role of serum amyloid P component in bacterial infection: protection of the host or protection of the pathogen.
8/2000Renal transplantation for amyloid end-stage renal failure-insights from serial serum amyloid P component scintigraphy.
6/2000Human serum amyloid P component is a single uncomplexed pentamer in whole serum.
5/2000Curative hepatorenal transplantation in systemic amyloidosis caused by the Glu526Val fibrinogen alpha-chain variant in an English family.

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M B Pepys Research Topics

Disease

8Amyloid Plaque
12/2007 - 05/2000
8Amyloidosis
12/2007 - 05/2000
4Myocardial Infarction
10/2008 - 03/2001
4Infections
12/2007 - 07/2000
3Acute-Phase Reaction
10/2008 - 07/2001
3Coronary Disease (Coronary Heart Disease)
10/2008 - 07/2000
3Bacterial Infections (Bacterial Infection)
04/2005 - 06/2000
2Scrapie
12/2007 - 04/2001
2Prion Diseases (Transmissible Spongiform Encephalopathies)
12/2007 - 07/2000
2Chronic Kidney Failure (Chronic Renal Failure)
10/2006 - 08/2000
2Atherosclerotic Plaque (Atheroma)
11/2003 - 03/2001
2Alzheimer Disease (Alzheimer's Disease)
05/2002 - 07/2000
2Type 2 Diabetes Mellitus (MODY)
05/2002 - 07/2000
2Hypertension (High Blood Pressure)
03/2001 - 12/2000
2Inflammation (Inflammations)
03/2001 - 12/2000
1Wounds and Injuries (Trauma)
10/2006
1Cytomegalovirus Infections (Inclusion Disease)
10/2006
1Disease Progression
10/2006
1Stable Angina
06/2004
1Unstable Angina
06/2004
1Coronary Restenosis
06/2004
1Cardiovascular Diseases (Cardiovascular Disease)
11/2003
1Castleman Disease (Castleman's Disease)
04/2002
1Insulin Resistance
07/2001
1Abdominal Obesity
07/2001
1Atherosclerosis
03/2001
1Thrombosis (Thrombus)
03/2001
1Metabolic Syndrome (Dysmetabolic Syndrome X)
12/2000
1Osteoarthritis
07/2000
1Liver Failure
05/2000
1Immunoglobulin Light-chain Amyloidosis
05/2000
1Metabolic Diseases (Metabolic Disease)
05/2000

Drug/Important Bio-Agent (IBA)

9C-Reactive ProteinIBA
10/2008 - 07/2000
8Amyloid (Amyloid Fibrils)IBA
12/2007 - 05/2000
6Serum Amyloid P-ComponentIBA
05/2002 - 05/2000
5Acute-Phase Proteins (Acute-Phase Protein)IBA
10/2008 - 07/2000
5Proteins (Proteins, Gene)FDA Link
12/2007 - 07/2000
2Interleukin-6 (Interleukin 6)IBA
04/2005 - 06/2004
2Serum Amyloid A Protein (Serum Amyloid A)IBA
06/2004 - 07/2001
2Pharmaceutical PreparationsIBA
05/2002 - 12/2000
2AA amyloidosisIBA
04/2002 - 07/2001
2Amyloidogenic ProteinsIBA
07/2001 - 05/2000
2Complement System Proteins (Complement)IBA
04/2001 - 03/2001
1PrionsIBA
12/2007
1Peptide Hydrolases (Proteases)FDA Link
12/2007
1Prion ProteinsIBA
12/2007
1PrPSc ProteinsIBA
12/2007
1Apolipoprotein A-I (Apolipoprotein A1)IBA
10/2006
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
04/2005
1Lipoproteins (Lipoprotein)IBA
11/2003
1Biological ProductsIBA
11/2003
1Blood Proteins (Serum Proteins)IBA
05/2002
1Particulate MatterIBA
07/2001
1LDL CholesterolIBA
03/2001
1LDL Lipoproteins (beta Lipoproteins)IBA
03/2001
1Carboxylic AcidsIBA
12/2000
1pyrrolidineIBA
12/2000
1Triglycerides (Triacylglycerol)IBA
12/2000
1CholesterolIBA
12/2000
1HDL CholesterolIBA
12/2000
1Uric Acid (Urate)IBA
12/2000
1ChromatinIBA
06/2000
1Fibrinogen (Factor I)FDA Link
05/2000
1Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA
05/2000

Therapy/Procedure

3Transplantation
10/2006 - 05/2000
2Kidney Transplantation
10/2006 - 08/2000
1Organ Transplantation
10/2006
1Stents
06/2004
1Liver Transplantation
05/2000